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. Author manuscript; available in PMC: 2015 Jul 20.
Published in final edited form as: Nat Commun. 2015 Jan 20;6:6100. doi: 10.1038/ncomms7100

Figure 3. The CD69 expression of Ivag vs IV transferred naïve OT-I CD8+ T cells in wild type and LN-deficient LTαKO mice at 24 hours PI.

Figure 3

(a) The dual transfer model. (b)The experimental design. (c to e) The CD69 expression of transferred naïve OT-I CD8+ T cells in the vaginal mucosa and iliac LNs of WT mice. This is representative of 3 independently repeat experiments (n=5 for WT animals; n=3 for LTαKO animals) with the same results. (c) The total and CD69-expressing transferred naïve OT-I CD8+ T cell in the vaginal mucosa. (d) The total and CD69-expressing transferred naïve OT-I CD8+ T cell in the iliac LNs. (e) The percentage (mean ± SEM) of CD69 expression in each group. (f to h) The total and CD69-expressing transferred naïve OT-I CD8+ T cells in the vaginal mucosa and liver of LN-deficient LTαKO mice. This is representative of 2 independently repeated experiments with the same results. (f) The total and CD69-expressing transferred naïve OT-I CD8+ T cell in vaginal mucosa of LTα KO mice. (g) The total and CD69-expressing transferred naïve OT-I CD8+ T cell in liver of LTαKO mice. (h) The percentage (mean ± SEM) of CD69 expression in each group. The p value was generated using a Student’s t test.