Table 5.
First-line treatment | High second-line treatment | Low second-line treatment | |
---|---|---|---|
Manic episode | AAP/MS monotherapy MS plus AAP |
MS plus LTG/TAP/other AAP MS plus LTG plus AAP/other AAP/TAP ECT TAP monotherapy |
|
Depressive episode | AAP monotherapy AAP plus MS/LTG |
MS/LTG monotherapy MS plus LTG/AD |
TAP/AD monotherapy AD plus AAP/LTG TAP plus MS/AD MS plus AD plus TAP MS plus AAP plus LTG/AD MS plus AAP plus LTG plus AD ECT |
Note: Bold: no consensus.
Abbreviations: AAP, atypical antipsychotics; AD, antidepressant; ECT, electroconvulsive therapy; LTG, lamotrigine; MS, mood stabilizer; TAP, typical antipsychotics.