Table 1.
Hits | Symbol | Gene name | Function |
---|---|---|---|
13 | BZW2 | Basic leucine zipper and W2 domains 2 | Transcription/Translation |
10 | RBPJ | Recombination signal binding protein for immunoglobulin kappa J region | |
10 | SPOP | Speckle-type POZ protein | |
2 | EIF4G3 | Eukaryotic translation initiation factor 4 gamma, 3 | |
2 | ZHX1 | Zinc fingers and homeoboxes 1 | |
2 | PNO1 | Partner of NOB1 homolog | |
2 | SON | SON DNA binding protein | |
1 | ARID4B | AT rich interactive domain 4B (RBP1-like) | |
1 | SUPT6H | Suppressor of Ty 6 homolog | |
3 | TNKS1 | Tankyrase 1 | Protein homeostasis |
2 | KAZN | Kazrin, periplakin interacting protein | |
1 | WIPI1 | WD repeat domain, phosphoinositide interacting 1 | |
1 | TNKS2 | Tankyrase 2 | |
1 | KDM6B | Lysine (K)-specific demethylase 6B | |
1 | L1CAM | L1 cell adhesion molecule | Migration/Invasion |
1 | IQGAP1 | IQ motif containing GTPase activating protein 1 | |
10 | MCCC1 | Methylcrotonoyl-CoA carboxylase 1 (alpha) | Metabolism |
2 | AHNAK2 | AHNAK nucleoprotein 2 | |
2 | ETNK | Ethanolamine kinase | |
2 | NDUFA11 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11 | |
1 | UEVLD | UEV and lactate/malate dehyrogenase domains | |
8 | EPRS | Glutamyl-prolyl-tRNA synthetase | Cell cycle |
4 | GOLGA4 | Golgi autoantigen, golgin subfamily a, 4 | |
3 | NCAPD2 | Non-SMC condensin I complex, subunit D2 | |
2 | TACC2 | Transforming, acidic coiled-coil containing protein 2 | |
1 | CKAP2 | Cytoskeleton associated protein 2 | |
1 | KIF15 | Kinesin family member 15 | |
1 | BubR1 | Bub1-related kinase | |
2 | PARP2 | Poly (ADP-ribose) polymerase family, member 2 | Others |
1 | FLVCR1 | Feline leukemia virus subgroup C cellular receptor 1 | |
1 | KBP | KIF1 binding protein | |
1 | SILV (gp100) | Premelanosome protein | |
1 | TPM3 | Tropomyosin 3 | |
1 | DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | |
1 | CLMN | Calmin | Unknown |
1 | INADL | InaD-like |
Red denotes gene products identified in screens with two independent AML patient sera samples.