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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Clin Cancer Res. 2014 Dec 23;21(5):1010–1018. doi: 10.1158/1078-0432.CCR-14-1956

Table 1.

Targets identified in K008 cDNA expression library with sera from vaccinated AML patients

Hits Symbol Gene name Function
13 BZW2 Basic leucine zipper and W2 domains 2 Transcription/Translation
10 RBPJ Recombination signal binding protein for immunoglobulin kappa J region
10 SPOP Speckle-type POZ protein
2 EIF4G3 Eukaryotic translation initiation factor 4 gamma, 3
2 ZHX1 Zinc fingers and homeoboxes 1
2 PNO1 Partner of NOB1 homolog
2 SON SON DNA binding protein
1 ARID4B AT rich interactive domain 4B (RBP1-like)
1 SUPT6H Suppressor of Ty 6 homolog
3 TNKS1 Tankyrase 1 Protein homeostasis
2 KAZN Kazrin, periplakin interacting protein
1 WIPI1 WD repeat domain, phosphoinositide interacting 1
1 TNKS2 Tankyrase 2
1 KDM6B Lysine (K)-specific demethylase 6B
1 L1CAM L1 cell adhesion molecule Migration/Invasion
1 IQGAP1 IQ motif containing GTPase activating protein 1
10 MCCC1 Methylcrotonoyl-CoA carboxylase 1 (alpha) Metabolism
2 AHNAK2 AHNAK nucleoprotein 2
2 ETNK Ethanolamine kinase
2 NDUFA11 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11
1 UEVLD UEV and lactate/malate dehyrogenase domains
8 EPRS Glutamyl-prolyl-tRNA synthetase Cell cycle
4 GOLGA4 Golgi autoantigen, golgin subfamily a, 4
3 NCAPD2 Non-SMC condensin I complex, subunit D2
2 TACC2 Transforming, acidic coiled-coil containing protein 2
1 CKAP2 Cytoskeleton associated protein 2
1 KIF15 Kinesin family member 15
1 BubR1 Bub1-related kinase
2 PARP2 Poly (ADP-ribose) polymerase family, member 2 Others
1 FLVCR1 Feline leukemia virus subgroup C cellular receptor 1
1 KBP KIF1 binding protein
1 SILV (gp100) Premelanosome protein
1 TPM3 Tropomyosin 3
1 DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
1 CLMN Calmin Unknown
1 INADL InaD-like

Red denotes gene products identified in screens with two independent AML patient sera samples.