Table 2. Effects of acute ethanol on pERK-positive cells counts over time.

	10 minutes		30 minutes		90 minutes
Brain region	Saline	Ethanol	Saline	Ethanol	Saline	Ethanol
Nucleus Accumbens
Core	298.5 ± 75.30	42.13 ± 7.182*	82.67 ± 20.22	37.35 ± 6.211*	156.8 ± 34.71	89.58 ± 13.23
Shell	366.3 ± 100.5	218.2 ± 39.3	91.84 ± 25.58	158.3 ± 40.16	456.0 ± 84.43	574.6 ± 209.5
Amygdala
Basolateral	146.3 ± 19.82	136.9 ± 30.49	28.05 ± 9.167	42.79 ± 10.47	9.394 ± 2.630	44.57 ± 15.49
Central	652.9 ± 128.8	1188 ± 108.3*	276.2 ± 59.35	708.3 ± 104.5*	167.0 ± 55.46	240.7 ± 68.06
Prefrontal Cortex	282.0 ± 57.38	466.9 ± 26.67*	109.5 ± 64.56	446.9 ± 39.31*	127.3 ± 41.57	136.2 ± 33.47
Cingulate Cortex	109.0 ± 16.23	143.7 ± 19.71	54.02 ± 24.45	172.2 ± 19.66*	39.69 ± 12.12	49.17 ± 15.42
Insular Cortex	125.5 ± 10.74	135.4 ± 11.33	29.42 ± 17.29	64.67 ± 11.95	36.46 ± 11.27	42.75 ± 12.40
Piriform Cortex	80.85 ± 18.21	245.7 ± 43.06*	109.1 ± 34.26	78.47 ± 25.55	11.61 ± 5.962	14.46 ± 8.162
PVN Thalamus	248.0 ± 26.62	437.3 ± 64.46*	87.19 ± 50.12	187.2 ± 53.07	42.02 ± 12.41	175.9 ± 41.05*
Bed stria terminalis	249.1 ± 62.44	731.9 ± 128.7	245.2 ± 109.4	649.9 ± 153.8	20.31 ± 6.484	213.5 ± 98.19

Mean number (± SEM) of pERK1/2 positive cells following saline or 3.0 g/kg ethanol treatment expressed as counts/mm2.

^*Significantly different from saline control at the given time point (p<0.05; Student’s t-test).