CRH administration and FAAH inhibition on anxiety-like behavior. A–G, Effects of vehicle, CRH (10 ng), FAAH inhibition (URB597; 10 ng), or CRH + URB597, 30 min before testing on the EPM on (A) open arm time, (B) percentage open arm time, (C) closed arm time, (D) percentage closed arm time, (E) total entries, (F) percentage open arm entries, and (G) circulating plasma CORT levels 30 min following EPM testing. H, Representative photomicrograph showing injector placement (arrow). Scale bar, 350 μm. I, Illustration of coronal sections showing representative cannula placements. Data are mean + SEM; n = 10–14/group. *p < 0.05.