Table.
Characteristics of Monozygotic (MZ) and Dizygotic (DZ) Twin-Pairs at Time of Initial Diagnosis of Intracranial Aneurysm (IA)
| Age | Gender | HTN | Smoking (pack-years) | IA Location(s) and Size | Rupture | |
|---|---|---|---|---|---|---|
| MZ twin-pairs | ||||||
| 1 | 22 22 |
F F |
no no |
never never |
L ICA (unk), R ICA (6mm) L ICA (unk), AComm (unk) |
yes (L ICA) yes (L ICA) |
| 2 | 56 55 |
F F |
no yes |
former (43.5) former (3.6) |
L MCA (6mm), L AntChor (unk), Bas (unk), L SupHyp (3mm) L ICA (3mm) |
yes (record does not indicate which IA) no |
| 3 | 43 43 |
F F |
no no |
current (14.5) current (21.8) |
L ICA (7mm), L Ophth (1.5mm) not specified on report |
no yes |
| 4 | 41 27 |
M M |
yes no |
never never |
R ICA (3mm) R ICA (6mm) |
no yes |
| 5 | 32 31 |
F F |
no yes |
current (14.3) current (18) |
R MCA (unk), L MCA (unk) not specified on report |
no yes |
| 6 | 51 53 |
F F |
yes yes |
never never |
AComm (7mm) AComm (4mm) |
yes yes |
| 7 | 54 53 |
M M |
no no |
former (25.1) current (21) |
R ICA (7mm), L SupCer (3mm) L MCA (17mm), R PComm (5mm), AComm (unk) |
no no |
| 8 | 56 56 |
F F |
no no |
never never |
R ICA (8mm), Bas (3mm) L ICA (unk) |
no no |
| 9 | 45 44 |
F F |
no no |
current (20.3) current (11) |
R MCA (unk), R PComm (unk), AntChor (unk) R PComm (11mm) |
yes (R MCA) no |
| 10 | 68 66 |
F F |
no no |
former (14) former (34) |
L ICA (unk), L MCA (unk) L MCA (5mm), L ICA (2mm) |
no no |
| 11 | 50 42 |
F F |
no no |
current (17) current (20.3) |
MCA (report does not mention side or size) not specified on death certificate (unk) |
no yes |
| DZ twin-pairs | ||||||
| 1 | 64 64 |
F F |
no yes |
never current (43) |
R ICA (4.5mm) L MCA (2mm) |
no no |
| 2 | 61 60 |
F F |
yes yes |
former (8.7) never |
R ICA (8mm), R ICA (1mm) AComm (15mm) |
no yes |
| 3 | 46 46 |
F F |
no no |
former (16.5) former (5.8) |
L MCA (4mm), Bas (3mm) R MCA (7mm), R ACA (2.9mm), Bas (0.5mm) |
yes (Bas) no |
| 4 | 44 35 |
F F |
no no |
former (2) current (20) |
AComm (unk) L MCA (unk) |
no yes |
| 5 | 51 51 |
F F |
no yes |
former (17.8) current (34) |
L MCA (6mm), R MCA (2mm) AComm (3mm), L PComm (3mm) |
no no |
Note: IAs in bold type denote location concordance within twin-pairs.
ICA territory: ICA=internal carotid artery, PComm=posterior communicating artery, Ophth=ophthalmic artery, AntChor=anterior choroidal artery, SupHyp=superior hypophyseal artery.
MCA territory: MCA=middle cerebral artery.
ACA territory: ACA=anterior cerebral artery, AComm=anterior communicating artery.
Vertebrobasilar territory: Bas=basilar tip, SupCer=superior cerebellar artery
CTA: CT angiogram
Unk: unknown