Table 1.
Genotype Frequencies for triallelic coding of 5HTTLPR and rs25531 by race/ethnicity in the National Longitudinal Study of Adolescent to Adult Health (Add Health).
| Genotype (N, %) | |||||||
|---|---|---|---|---|---|---|---|
| Race/Ethnicity | N | L-A/L-A | L-A/L-G | L-A/S | L-G/L-G | L-G/S | S/S |
| White, Non-Hispanic | 7878 | 1982 (0.25) | 537 (0.07) | 3379 (0.43) | 38 (< 0.01) | 483 (0.06) | 1449 (0.18) |
| White, Hispanic | 981 | 207 (0.21) | 52 (0.05) | 411 (0.42) | -- | 58 (0.06) | 251 (0.26) |
| Black, Non-Hispanic | 3290 | 882 (0.27) | 769 (0.23) | 867 (0.26) | 128 (0.04) | 326 (0.10) | 261 (0.08) |
| Black, Hispanic | 90 | 19 (0.21) | 15 (0.17) | 31 (0.34) | 2 (0.02) | 7 (0.08) | 14 (0.16) |
| Asian, Non-Hispanic | 911 | 38 (0.04) | 41 (0.05) | 231 (0.25) | 15 (0.02) | 149 (0.16) | 405 (0.44) |
| Asian, Hispanic | 86 | 41 (0.08) | 3 (0.06) | 14 (0.26) | -- | 7 (0.13) | 21 (0.40) |
| Native American, Non-Hispanic | 273 | 61 (0.22) | 10 (0.04) | 127 (0.47) | -- | 12 (0.04) | 62 (0.23) |
| Native American, Hispanic | 126 | 24 (0.19) | 5 (0.04) | 49 (0.39) | -- | 5 (0.04) | 43 (0.34) |
| Mixed/Other, Non-Hispanic | 128 | 26 (0.20) | 18 (0.14) | 37 (0.29) | -- | 14 (0.11) | 32 (0.25) |
| Mixed/Other, Hispanic | 1074 | 194 (0.18) | 47 (0.04) | 481 (0.45) | 5 (< 0.01) | 60 (0.06) | 285 (0.27) |
Note: Not tabled are genotypes containing 103 ‘XL-alleles’: 57 (0.02) in Black, Non-Hispanic; 32 (0.04) in Asian, Non-Hispanic; 9 (< 0.01) European, Non-Hispanic; 2 (0.02) in Black, Hispanic; and 1 each among European-Hispanic, Asian-Hispanic, and Native American-Non-Hispanic.
HWE: White, Non-Hispanic: χ2 = 0.1697, df = 2, p = 0.9209; White, Hispanic: χ2 = 2.0234, df = 2, p = 0.3636; Black, Non-Hispanic: χ2 = 0.7165, df = 2, p = 0.6989; Black, Hispanic: χ2 = 0.1826, df = 2, p = 0.9127; Asian, Non-Hispanic: χ2 = 0.6745, df = 2, p = 0.7137; Asian, Hispanic: χ2 = 32.1833, df = 2, p < 0.0001; Native American, Non-Hispanic: χ2 = 0.0368, df = 2, p = 0.9817; Native American, Hispanic: χ2 = 1.8312, df = 2, p = 0.4002; Mixed/Other, Non-Hispanic: χ2 = 1.3909, df = 2, p = 0.4988; Mixed/Other, Hispanic: χ2 = 0.0489, df = 2, p = 0.9758.