Table 2. Physiologic parameters of groups.
| Groups | Blood pressure (mm Hg)a | rCBF during ischemia (%) | Tissue oxygen saturation (%) |
|---|---|---|---|
| TfRMAb-free, control | 93±7 (n=4) | 29±3 | 96±1 |
| z-DEVD | 95±4 (n=3) | 27±2 | 94±2 |
| bFGF | 90±5 (n=5) | 28±3 | 97±1 |
| bFGF and z-DEVD (pre-ischemia) | 83±10 (n=4) | 30±3 | 96±2 |
| bFGF and z-DEVD (3 hours post-ischemia) | 94±5 (n=3) | 25±4 | 95±3 |
| bFGF (intravenously) | 98±8 (n=5) | 26±3 | 96±2 |
| bFGF+imatinib | 94±3 (n=3) | 28±4 | 96±1 |
bFGF, basic fibroblast growth factor; rCBF, regional cerebral blood flow; TfRMAb, anti-transferrin receptor-1 monoclonal antibody; z-DEVD, benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethylketone.
Values are given as mean±s.e.m. Group means were not significantly different (P>0.05).
a
Blood pressure could not be measured in some mice for technical reasons. n=5–6 for rCBF and tissue oxygen saturation values. Physiologic parameters were recorded during the first 30 minutes of ischemia before terminating anesthesia.