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. 2015 Mar 2;18(1):19395. doi: 10.7448/IAS.18.1.19395

Table 2.

Measures of delay for the adult care cascade employed in the peer-reviewed literature

Testing/diagnosis Linkage/enrolment Retained in care Treatment Viral suppression
Peer-reviewed literature Late testing is commonly defined in the peer-reviewed literature in terms of concurrent diagnoses of HIV and AIDS [1519] or as a measurement of time between HIV and AIDS diagnosis [2024]. Late enrolment is defined in relation to the time between HIV diagnosis and presentation to a wide range of HIV-related services including enrolment, CD4 evaluation and treatment initiation. Different retention measures and their association with the likelihood of individuals achieving viral suppression have been employed [2528]. Late treatment is measured multiple ways. WHO and UNAIDS recommend treatment initiation when CD4 <500 cells/mm3 or with an AIDS-defining event, regardless of CD4 count at the time of treatment initiation. A majority of studies used thresholds in the 300–500 RNA copies/mL range [13].