Table 1. Particles lost and released after simulated use in in vitro vessel model.
Results | Statistical Analysis | ||||||
---|---|---|---|---|---|---|---|
Particle Size [μm] | Cetpyrsal/PTX-DCB | HA/PTX-DCB | PVP/PTX-DCB | Cetpyrsal/PTX- vs. HA/PTX-DCB | Cetpyrsal/PTX-vs. PVP/PTX-DCB | HA/PTX- vs. PVP/PTX-DCB | |
Number of particles lost during track [#/mm²] | ≥10 | 100 ± 106 | 418 ± 198 | 790 ± 191 | ** | ** | * |
≥25 | 16 ± 12 | 25 ± 9 | 53 ± 11 | n.s. | ** | ** | |
Number of particles transferred after dilatation [#/mm²] | ≥10 | 70 ± 37 | 37 ± 7 | 93 ± 53 | n.s. | n.s. | n.s. |
≥25 | 18 ± 10 | 3 ± 1 | 12 ± 7 | ** | n.s. | ** |
Number of particles (≥10 μm, ≥25 μm) per mm² balloon surface released from differently coated DCB after simulated use in an in vitro vessel model according to ASTM F2394-07, X.2.4. Values show mean ± SD of 5 experiments
n.s.: not significant
* significant: p<0.05
** very significant: p<0.01