Table 1.

SKI II Prevents LPS-Induced PTB and Spontaneous Abortion

Group	LPS control	SKI II treatment	Sham
LPS (50 mg/kg) received	Yes	Yes	No
No. of mice	7	7	3
No. of mice delivered	5	1∗	0
Total no. of pups	47	50	20
No. of pups spontaneously aborted	21	2∗∗∗∗	0

LPS, lipopolysaccharide; PTB, preterm birth; SKI II, sphingosine kinase inhibitor II.

^∗P < 0.05, ^∗∗∗∗P < 0.0001.