Skip to main content
. 2015 Mar;185(3):741–755. doi: 10.1016/j.ajpath.2014.11.006

Figure 5.

Figure 5

Cigarette smoke (CS) induces extracellular matrix (ECM) protein deposition around small airways and vessels in nonhuman primate (NHP) lungs. A and B: Lung sections from NHPs exposed to air or CS for 12 weeks immunostained with Masson's trichrome stain to visualize deposition of ECM proteins (visualized as blue staining) around small airways (A) and vessels (B) of NHPs exposed to CS for 12 weeks compared with NHPs exposed to air. C and D: Quantitation of ECM protein deposition around bronchi and small vessels, respectively, in air- and CS-exposed animals normalized to the length of the bronchial wall or the length of the vessel internal circumference, respectively. Data are means + SEM (C and D). n = 5 NHPs per group (C and D). ∗P < 0.05 versus air-exposed animals (C and D). Original magnification, ×200 (A and B).