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(A) Position of the UL54 and the UL97 open reading frame in the genome of HCMV strain TB40E [50]. (B) UL54 open reading frame with conserved subdomains (black boxes) of the gene. Mutations can lead to resistance to GCV, CDV or PFA and can also cause multidrug resistance. (C) UL97 open reading frame including the conserved subdomains (black boxes). Mutations in the UL97 gene can cause resistance to GCV.
