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Wound collagen IV staining. (a) shows collagen IV staining was lagging in untreated diabetic wounds at day 7; * P < 0.05 compared with Control + CTGF treated animals, by ANOVA. (b) shows at day 14 the CTGF treated diabetic animals showed significantly increased collagen IV compared with the other groups; * P < 0.05 by ANOVA. Results are expressed as mean ± SEM.
