Table 4.
A comparison between the baseline characteristics of the RAGE G82S genotypes and alleles in the AAA patient and control groups.
| Characteristics | AAA patient group | Control group | P G a value | P A a value | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Genotype n (%) | Allele n (%) | Genotype n (%) | Allele n (%) | |||||||||
| GG | GS | SS | G | S | GG | GS | SS | G | S | |||
| Age | ||||||||||||
| ≥70 years | 103 (47.9) | 95 (44.2) | 17 (7.9) | 301 (70.0) | 129 (30.0) | 136 (57.9) | 84 (35.7) | 15 (6.4) | 356 (75.7) | 114 (24.3) | 0.11 | 0.052 |
| <70 years | 84 (50.6) | 60 (36.1) | 22 (13.3) | 228 (68.7) | 104 (31.3) | 122 (60.7) | 65 (32.3) | 14 (7.0) | 309 (76.9) | 93 (23.1) | 0.092 | 0.058 |
| Gender | ||||||||||||
| Male | 140 (47.9) | 119 (40.8) | 33 (11.3) | 399 (68.3) | 185 (31.7) | 131 (59.3) | 75 (33.9) | 15 (6.8) | 337 (76.2) | 105 (23.8) | 0.025b | 0.012b |
| Female | 47 (52.8) | 36 (40.4) | 6 (6.7) | 130 (73.0) | 48 (27.0) | 127 (59.1) | 74 (34.4) | 14 (6.5) | 328 (76.3) | 102 (23.7) | 0.59 | 0.40 |
| Smoking | ||||||||||||
| Yes | 91 (44.2) | 95 (46.1) | 20 (9.7) | 277 (67.2) | 135 (32.8) | 87 (60.0) | 50 (34.5) | 8 (5.5) | 224 (77.2) | 66 (22.8) | 0.020 | 0.008 |
| No | 96 (54.9) | 60 (34.3) | 19 (10.9) | 252 (72.0) | 98 (28.0) | 171 (58.8) | 99 (34.0) | 21 (7.2) | 441 (75.8) | 141 (24.2) | 0.37 | 0.20 |
| Diabetes | ||||||||||||
| Yes | 37 (41.6) | 43 (48.3) | 9 (10.1) | 117 (65.7) | 61 (34.3) | 51 (59.3) | 29 (33.7) | 6 (7.0) | 131 (76.2) | 41 (23.8) | 0.070 | 0.082 |
| No | 150 (51.4) | 112 (38.4) | 30 (10.3) | 412 (70.5) | 172 (29.5) | 207 (59.1) | 120 (34.3) | 23 (6.6) | 534 (76.3) | 166 (23.7) | 0.088 | 0.060 |
| Hypertension | ||||||||||||
| Yes | 69 (46.9) | 62 (42.2) | 16 (10.9) | 200 (68.0) | 94 (32.0) | 91 (58.7) | 54 (34.8) | 10 (6.5) | 236 (76.1) | 74 (23.9) | 0.093 | 0.056 |
| No | 118 (50.4) | 93 (39.7) | 23 (9.8) | 329 (70.3) | 139 (29.7) | 167 (59.4) | 95 (33.8) | 19 (6.8) | 429 (76.3) | 133 (23.7) | 0.10 | 0.069 |
P G: P value of the difference in alleles between the case and control groups; P A: P value of the difference in genotype between the case and control groups.
aAdjusted for age, gender, smoking, hypertension, diabetes mellitus, and dyslipidemia.
b P values under 0.05 were indicated in bold font.