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. 2015 Feb 18;2015:834736. doi: 10.1155/2015/834736

Table 3.

Hearing loss severity score stratified by different genotypes among the different gene variants: 44 (mild), 92 (moderate), 33 (severe), and 31 (profound). HL severity score is graded in the following: mild hearing loss (16–40 dB HL), moderate hearing loss (41–70 dB HL), severe hearing loss (71–90 dB HL), and profound hearing loss (>90).

Gene variant FPN1 (SLC40A1) Tf HFE HFE HEPC (HAMP)
−8CG C1, C2 H63D C282Y −582AG

Cases 200 200 200 200 200

Genotypes CC CG GG C1C1 C1C2 C2C2 HH HD DD CC CY AA AG GG

Total (n) 123 62 15 139 53 8 142 56 2 193 7 111 77 12

HL severity score (PTA dB HL)
16–40 dB HL 27 12 5 27 16 1 31 13 0 42 2 34 6 4
41–70 dB HL 60 26 6 66 24 2 62 28 2 88 4 51 35 6
71–90 dB HL 18 12 3 21 8 4 25 8 0 32 1 12 19 2
>90 dB HL 18 12 1 25 5 1 24 7 0 31 0 14 17 0