Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Oct 17;123(3):246–254. doi: 10.1289/ehp.1408524

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Publication of EHP lies in the public domain and is therefore without copyright. All text from EHP may be reprinted freely. Use of materials published in EHP should be acknowledged (for example, “Reproduced with permission from Environmental Health Perspectives”); pertinent reference information should be provided for the article from which the material was reproduced. Articles from EHP, especially the News section, may contain photographs or illustrations copyrighted by other commercial organizations or individuals that may not be used without obtaining prior approval from the holder of the copyright.

PMC Copyright notice

Long-term exposure to B[a]P showed no detectable effects on HCC cell growth. (A) BEL-7404 (left) and SMMC-7721 (right) cells were treated with 0.1% DMSO or different concentrations of B[a]P for 1 month, and cell growth was evaluated by the CCK-8 assay; values are mean ± SD (n = 6/group). (B) BEL-7404 cells were treated with 0.1% DMSO or B[a]P for 1 month and harvested for cell cycle distribution analysis by flow cytometry. Red areas represent G₁/S and G₂/M phases; arrowheads indicate the peaks of G₁/S and G₂/M phases. (C) Soft agar assay of BEL-7404 cells exposed to 0.1% DMSO or different concentrations of B[a]P for 1 month. Bars = 1 mm for 4× magnification (top), 400 μm for 10× magnification (center), and 200 μm for 20× magnification (bottom).