Figure 3.

Effect of Isorhamnetin, cisplatin, carboplatin and their combinations on cell apoptosis in A-549 cancer cells. Control (Untreated) A-549 cells after 48 h showed normal structure without noticeable apoptosis. (B-D) Isorhamnetin, cisplatin and carboplatin-treated cells respectively showed early apoptosis features including blebbing and chromatin condensation after 48 h treatment. (E and F) isorhamnetin+cisplatin and isorhamnetin+carboplatin-treated cells respectively showed late apoptosis in addition to early apoptotic features. (magnification: 200×).