Table 2.
Association between CREB1 SNPs and MDD susceptibility
| rs number | Genotype | MDD | Control | OR (95% CI) | ORa (95% CI) |
|---|---|---|---|---|---|
| rs11904814 | TT | 83 | 86 | 1 | |
| TG | 300 | 287 | 1.08 (0.77-1.53) | 1.12 (0.76-1.65) | |
| GG | 203 | 213 | 0.99 (0.69-1.42) | 1.04 (0.69-1.55) | |
| rs6740584 | TT | 206 | 220 | 1 | |
| TC | 299 | 282 | 1.13 (0.88-1.45) | 1.15 (0.86-1.53) | |
| CC | 81 | 84 | 1.03 (0.72-1.48) | 1.00 (0.66-1.49) | |
| rs2253206 | GG | 86 | 89 | 1 | |
| GA | 293 | 286 | 1.06 (0.76-1.49) | 1.08 (0.74-1.59) | |
| AA | 207 | 211 | 1.02 (0.71-1.45) | 1.04 (0.70-1.55) | |
| rs2551941 | AA | 105 | 111 | 1 | |
| AT | 293 | 281 | 0.87 (0.63-1.20) | 1.12 (0.79-1.60) | |
| TT | 188 | 194 | 0.76 (0.54-1.07) | 1.04 (0.71-1.52) |
a
Adjusted by age, gender, marital status, smoking, drinking, family harmony, working condition and childhood trauma.