Table 4.
Interaction between drinking and CREB1 genetic polymorphisms
| Variable | Case | Control | OR (95% CI) | ORa (95% CI) |
|---|---|---|---|---|
| rs11904814 | ||||
| TT and no drinking | 3 | 23 | 1 | 1 |
| TG or GG and no drinking | 21 | 88 | 1.83 (0.50-6.67) | 1.91 (0.41-8.97) |
| TT and drinking | 80 | 63 | 9.74 (2.80-33.90) | 11.67 (2.52-54.18) |
| TG or GG and drinking | 482 | 412 | 8.97 (2.67-30.09) | 11.52 (2.55-51.95) |
| rs6740584 | ||||
| TT and no drinking | 11 | 34 | 1 | 1 |
| TC or CC and no drinking | 13 | 77 | 0.52 (0.21-1.28) | 0.61 (0.24-1.59) |
| TT and drinking | 195 | 186 | 3.24 (1.60-6.58) | 4.18 (1.87-9.38) |
| TC or CC and drinking | 367 | 289 | 3.93 (1.96-7.88) | 5.02 (2.27-11.14) |
| rs2553206 | ||||
| GG and no drinking | 2 | 24 | 1 | 1 |
| GA or AA and no drinking | 22 | 87 | 3.034 (0.666-13.825) | 1.22 (0.32-4.59) |
| GG and drinking | 84 | 65 | 15.51 (3.54-68.01) | 7.58 (2.05-27.98) |
| GA or AA and drinking | 478 | 410 | 13.99 (3.29-59.55) | 7.59 (2.12-27.14) |
| rs2551941 | ||||
| AA and no drinking | 4 | 29 | 1 | 1 |
| AT or TT and no drinking | 20 | 82 | 1.77 (0.56-5.61) | 1.33 (0.45-3.89) |
| AA and drinking | 101 | 82 | 8.93 (3.02-26.43) | 8.37 (3.02-23.23) |
| AT or TT and drinking | 461 | 393 | 8.50 (2.96-24.40) | 7.84 (2.93-20.98) |