Table 1.
Association of MAGE-A9 expression with clinical characteristics of NSCLC
| Groups | No. | Cytoplasm staining of MAGE-A9 | Interstitial staining of MAGE-A9 | ||||||
|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||
| Low or no expression (%) | High expression (%) | Pearson X2 | P value | Low or no expression (%) | High expression (%) | Pearson X2 | P value | ||
| Total | 213 | 102 (47.89) | 111 (52.11) | 115 | 98 (37.0) | ||||
| Gender | |||||||||
| Male | 160 | 72 (45.00) | 88 (55.00) | 2.1481 | 0.143 | 87 (54.37) | 73 (45.630) | 0.0382 | 0.845 |
| Female | 53 | 30 (56.60) | 23 (43.40) | 28 (52.83) | 25 (41.17) | ||||
| Age | |||||||||
| ≤ 60 years | 71 | 33 (46.48) | 38 (53.52) | 0.0847 | 0.771 | 45 (63.38) | 26 (36.62) | 3.7799 | 0.052 |
| > 60 years | 142 | 69 (48.59) | 73 (51.41) | 70 (49.30) | 72 (50.70) | ||||
| Differentiation | |||||||||
| Well and Moderately | 141 | 66 (46.81) | 75 (53.19) | 0.1130 | 0.737 | 75 (53.19) | 66 (46.81) | 0.0659 | 0.797 |
| Poorly | 69 | 34 (49.28) | 35 (50.72) | 38 (55.07) | 31 (44.93) | ||||
| Unknown | 3 | 2 | 1 | 2 | 1 | ||||
| Tumor size | |||||||||
| ≤ 3 cm | 74 | 44 (59.46 ) | 30 (40.54) | 7.8410 | 0.005* | 39 (52.70) | 35 (47.30) | 0.0024 | 0.961 |
| > 3 cm | 128 | 50 (39.06) | 78 (60.94) | 67 (52.34) | 61 (47.66) | ||||
| Unknown | 11 | 8 | 3 | 9 | 2 | ||||
| Histological type | |||||||||
| Squamous cell carcinoma | 141 | 61 (43.26) | 80 (56.74) | 4.7222 | 0.030* | 82 (58.16) | 59 (41.84) | 4.5969 | 0.032* |
| Adenocarcinoma | 60 | 36 (60.00) | 24 (40.00) | 25 (41.67) | 35 (58.33) | ||||
| Other | 12 | 5 | 7 | 8 | 4 | ||||
| Lymph node metastasis | |||||||||
| No regional lymph node metastasis | 128 | 69 (53.91) | 59 (46.09) | 6.1128 | 0.047* | 70 (54.69) | 58 (45.31) | 0.2436 | 0.885 |
| Metastasis in ipsilateral peribronchial | 49 | 20 (40.82) | 29 (59.18) | 26 (53.060) | 23 (46.94) | ||||
| Metastasis in mediastinal | 34 | 11 (32.35) | 23 (67.65) | 17 (50.00) | 17 (50.00) | ||||
| Unknown | 2 | 2 | 2 | ||||||
| TNM Classification | |||||||||
| I | 74 | 45 (60.81) | 29 (39.19) | 7.6263 | 0.022* | 39 (52.70) | 35 (47.30) | 0.2577 | 0.879 |
| II | 121 | 50 (41.32) | 71 (58.68) | 67 (55.37) | 54 (44.63) | ||||
| III and IV | 18 | 7 (38.89) | 11 (61.11) | 9 (50.00) | 9 (50.00) | ||||
NSCLC, non-small cell lung cancer.
*
P < 0.05.