Table 2.
Univariate and multivariable analyses of prognostic factors in NSLCL for 5-year survival
| Variable | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
|
| ||||||
| HR | P value | 95% CI | HR | P value | 95% CI | |
| Cytoplasm expression of MAGE-A9 | ||||||
| High versus low | 3.104 | 0.001* | 2.263-4.257 | 2.334 | 0.001* | 1.664-3.274 |
| Stromal expression of MAGE-A9 | ||||||
| High versus low | 2.283 | 0.001* | 1.668-3.123 | 1.942 | 0.001* | 1.407-2.681 |
| Gender | ||||||
| Male versus female | 0.843 | |||||
| Age (years) | ||||||
| < 60 versus ≥ 60 | 0.645 | |||||
| Tumor size (cm) | ||||||
| ≤ 3 versus > 3 | 1.488 | 0.017* | 1.073-2.063 | 0.914 | 0.648 | 0.884-11.448 |
| Differentiation | ||||||
| Well and mod versus poorly | 0.252 | |||||
| Histological type | ||||||
| Squamous cell carcinoma versus adenocarcinoma | 0.256 | |||||
| Lymph node metastasis | ||||||
| No regional lymph node versus MIP versus MIM | 1.432 | 0.001* | 1.170-1.754 | 1.200 | 0.089 | 0.973-1.481 |
| TNM classification | ||||||
| stage I versus stage II versus stage III/IV) | 1.320 | 0.011* | 1.064-1.637 | 1.403 | 0.021* | 1.053-1.870 |
CI, confidence interval; HR, hazard ratio; MIM, metastasis in mediastinal; MIP, metastasis in ipsilateral peribronchial; NSCLC, non-small cell lung cancer.