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The overexpression of miR-182 reversed the effect of fentanyl in HCT116 cells. HCT116 cells treated by fentanyl were transfected with or without the miR-182 mimic. MMP-9 expression were detected by Western blotting (A). The cell invasion was evaluated with Transwell chamber (B). *P < 0.05 by Student’s t-test, indicates a significant difference. All experiments were repeated three times.
