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. 2015 Jan 13;5(3):385–398. doi: 10.1534/g3.114.016501

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Copyright © 2015 Rowan et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution Unported License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Evaluation of Trained Individual GenomE Reconstruction (TIGER) on simulated data. The TIGER pipeline was applied to simulated read data from 1000 simulated recombinant individuals for three different coverage rates. For each coverage rate, the samples were subset into 10 bins of 100 individuals and genotypes and crossovers (COs) were predicted using TIGER pipeline within the bins. The first row of plots shows the difference between the expected (simulated) and predicted CO numbers for each coverage rate. The second row of plots shows the resolution of COs in marker space for each of the 10 bins. The x-axes indicate the distance between the predicted and expected CO point based on the number of markers with a false genotype prediction and the y-axes show the percentage of total COs. The same representation is presented in the last row of plots, except the x-axes are measured in physical distances (Mb).