Figure 1.

Effector function of T cells. Proliferation of T cells (A) in response to anti-CD3 antibody was assessed by tritiated thymidine [³H] incorporation. Stimulation index (SI) was calculated by dividing the mean cpm of stimulated T cells (in response to 1 μg/ml anti-CD3) by the mean cpm of unstimulated cells (in media alone). Anti-CD3-stimulated IL-2 (B) and IFN-γ (C) secretion from T cells was measured by ELISA. Data are presented as mean ± SEM. T-cell proliferation was significantly correlated with IL-2 secretion [(D); Spearman r = 0.3751, p = 0.0264], but not with IFN-γ secretion [(E); Spearman r = 0.0689, p = 0.6941].