Table 1.
Change in Mypt1 E24 splice variant ratios in animal models of vascular disease. Abbreviation definitions can be found in the abbreviations section of the text
| Model | Description | Change in Myptl isoform ratio |
Vessel studied |
Reference |
|---|---|---|---|---|
| Portal hypertension | PV stenosis | ↑ E24-out/E24-in | Portal vein, MA1s | [53] |
| HF/LF | MA2 ligation | ↑ E24-out/E24-in | MA1s | [75] |
| Pregnancy | No | Uterine artery | [40] | |
| Hypertension pregnancy | l-NAME | ↑ E24-out/E24-in | Uterine artery | [40] |
| Hypertension | l-NAME or AngII | No | Uterine artery, MAs | [40] and (JR Reho and SA Fisher, unpublished data) |
| Chronic coronary occlusion | Occlusion of LCx | No | Coronary arteries and arterioles |
X Zheng and SA Fisher, unpublished data |