Table 1.
Basic Characteristics of the Study Patients
| Characteristics | All patients (n =624) |
MDD (n =96) |
No MDD (n =528) |
p value |
|---|---|---|---|---|
| Age, years (IQR) | 43 (32–49) | 41 (30–48) | 43 (33–50) | 0.12 |
| Male Sex | 432 (69%) | 65 (68%) | 367 (70%) | 0.73 |
| Race White | 169 (27%) | 15 (16%) | 154 (29%) | < 0.05 |
| African American | 426 (68%) | 78 (81%) | 348 (66%) | |
| Other | 29 (5%) | 3 (3%) | 26 (5%) | |
| Years from HIV diagnosis (IQR) | 8.0 (3.1–13.0) | 8.0 (3.2–13.0) | 7.8 (2.8–14.0) | 0.89 |
| CD4 cell count * | 117 (19%) | 25 (29%) | 92 (19%) | < 0.05 |
| < 200 cells/mm3 | ||||
| HIV RNA Level * | 240 (38%) | 47 (55%) | 193 (40%) | < 0.05 |
| > 400 copies/mL | ||||
| Risky Sexual Behavior | 117 (19%) | 21 (22%) | 96 (18%) | 0.39 |
| Illicit Drug Use | 169 (27%) | 34 (35%) | 135 (26%) | < 0.05 |
| High-risk Drinking | 55 (9%) | 13 (22%) | 56 (16%) | 0.27 |
| Tobacco Use | 239 (47%) | 63 (66%) | 230 (44%) | < 0.001 |
| Currently on cART | 479 (77%) | 63 (66%) | 416 (79%) | < 0.01 |
| VAS < 95% | 123/479 (26%) | 24/63 (38%) | 99/416 (24%) | < 0.01 |
| PI-based cART | 237/479 (49%) | 36/63 (57%) | 201/416 (48%) | 0.19 |
| NNRTI-based cART | 208/479 (43%) | 25/63 (40%) | 183/416 (44%) | 0.52 |
| HIV RNA Level > 400 copies/mL on cART | 112/479 (23%) | 19/63 (30%) | 93/416 (22%) | < 0.05 |
MDD, major depressive disorder; IQR, interquartile range, cART, combination antiretroviral therapy; VAS, visual analogue scale; PI, protease inhibitor; NNRTI, non-nucleoside reverse transcriptase inhibitor.
*
Numbers and percentages include patients not on cART