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A. Common structural domains of POU transcription factors, including Octamer-binding factors (Octs). AA, amino acids; POUs, POU-specific domain; WFC, WFC motif. B. Crystal structure of DNA binding of the POU-specific domain and the POU-homeodomain (POUH). The helices (H) of each POU domain and the N- and C-termini are labeled. B is adapted from (37).
