Figure 3.

Time- and concentration dependent uptake of free Magnevist into F98 and LN229 cells. (A) LN229 and F98 glioma cells were incubated with Magnevist solution (0.34 mg/ml) for time periods of 1 to 24 h. (B) F98 cells were incubated with different concentrations of Magnevist solution (0.18 to 0.9 mg/ml) for 24 and 48 h, respectively. Resulting Gd-concentration in the cells was determined via ICP-MS, n = 3.