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. Author manuscript; available in PMC: 2015 Mar 4.
Published in final edited form as: J Inorg Biochem. 2007 May 8;101(10):1347–1353. doi: 10.1016/j.jinorgbio.2007.04.013

Fig. 2.

Fig. 2

Cell survival studies and LC50 determination. Survival of drug-sensitive KB-3-1 and Pgp- expressing KB-8-5 cells grown in the presence of chemotherapeutic agent, colchicine (25μM; positive control), increasing amount of metallodrug 5 (2A, top), and gallium(III) nitrate (2B, bottom). Data for the gallium(III) nitrate is replotted for comparison from reference [41]. Cells grown in the presence of vehicle alone served as control preparations; data for cell survival in the presence of metallodrug 5 or gallium(III) nitrate was plotted as a percent of vehicle control. LC50 (μM): 5, KB-3-1, 1.93; KB-8-5, >100. Each point represents the mean value of triplicate determinations; bars represent ± SEM when larger than symbol.