Table 5.
Comparison of interferon score and type I interferon activity measured in serum of mutation positive patients, by patient number
| Gene | Age at sampling (years) |
Interferon score |
Serum interferon activity (IU/mL) |
|
|---|---|---|---|---|
| AGS044 | TREX1 | 13·21 | 30·999 | 50, 9* |
| AGS060 | TREX1 | 12·93 | 12·954 | <3 |
| AGS205 | TREX1 | 22·07 | 20·360 | 6 |
| AGS635 | TREX1 | 174 | 17·557 | 100 |
| AGS015 | RNASEH2B | 12·01 | 2·149 | <3 |
| AGS068 | RNASEH2B | 7·73 | 10·371 | 12 |
| AGS068 | RNASEH2B | 8·05 | 8·163 | 5 |
| AGS266 | RNASEH2B | 5·19 | 61764 | 25 |
| AGS534 | RNASEH2B | 0·96 | 11·020 | 50 |
| AGS081_P1 | ADAR | 1578 | 45·676 | 12 |
| AGS081_P3 | ADAR | 5·28 | 21·590 | 12 |
| AGS251 | ADAR | 9·27 | 12·301 | <2, <3* |
| AGS430_P1 | ADAR | 5·53 | 14·306 | 5, 3* |
| AGS430_P2 | ADAR | 5·53 | 21·538 | 6 |
*
Measurements repeated in a separate aliquot of serum taken on the same day of sampling.