Table 1. Antimicrobial susceptibility profiles of uropathogenic Escherichia coli.
Class | Antimicrobial agents (mg/l) | NTUVH (n=69) | NCYUVTH (n=45) | Overall E. coli (n=114) | ||||||
---|---|---|---|---|---|---|---|---|---|---|
MIC50 | MIC90 | R%a,b) | MIC50 | MIC90 | R% a,b) | MIC50 | MIC90 | R% a,b) | ||
Aminoglycosides | Amikacin | 2 | 8 | 0 | 4 | 8 | 0 | 2 | 8 | 0 |
Gentamicin | 1 | 2 | 8.7 | 1 | 64 | 13.3 | 1 | 64 | 10.5 | |
Cephalosporins | Cefazolin | 2 | 16 | 0 | 2 | 8 | 0 | 2 | 8 | 0 |
Cefotaxime | 1 | 1 | 0 | 1 | 2 | 0 | 1 | 2 | 0 | |
Ceftazidime | 2 | 2 | 0 | 1 | 2 | 0 | 2 | 2 | 0 | |
Ceftiofur | 1 | 1 | 0 | 0.5 | 1 | 0 | 0.5 | 1 | 0 | |
Penicillins | Ampicillin | 512 | >1024 | 60.9 | 16 | 1024 | 33.3 | 16 | >1024 | 50 |
Amoxicillin | >1024 | >1024 | 56.5 | 8 | >1024 | 26.7 | 16 | >1024 | 44.7 | |
Amoxicillin-clavulanic acid | 8/4 | 16/8 | 0 | 8/4 | 16/8 | 6.7 | 8/4 | 16/8 | 2.6 | |
Phenicols | Chloramphenicol | 16 | 512 | 43.5 | 8 | 32 | 13.3 | 8 | 512 | 31.6 |
Florfenicol c) | 4 | 8 | 34.8 | 4 | 16 | 26.7 | 4 | 16 | 31.6 | |
Polymyxins | Colistin | 1 | 1 | 0 | 1 | 2 | 0 | 1 | 2 | 0 |
Quinolones | Ciprofloxacin | <0.125 | 0.25 | 0 | <0.125 | 32 | 13.3 | 0.125 | 0.25 | 5.3 |
Enrofloxacin c) | 0.25 | 0.5 | 0 | <0.125 | 32 | 13.3 | 0.125 | 1 | 5.3 | |
Nalidixic acid | 8 | 512 | 43.5 | 8 | >1024 | 33.3 | 8 | 1024 | 38.6 | |
Sulfonamides | Sulfamethoxazole-trimethoprim | 4/76 | >1024 | 43.5 | 1/19 | >1024 | 20 | 2/38 | >1024 | 34.2 |
Tetracyclines | Doxycycline | 8 | 128 | 39.1 | 2 | 32 | 26.7 | 4 | 128 | 28.9 |
Oxytetracycline | 256 | 1024 | 73.9 | 8 | 1024 | 40 | 8 | 1024 | 60.5 |
a) MIC breakpoints according to CLSI guidelines. b) Percentage of resistant isolates. c) Because the MIC breakpoints for UTIs were not provided in the 2007 CLSI guidelines, the values for bovine respiratory pathogens were used [10].