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IKKβ regulates macrophage phagocytosis. GFP-expressing macrophages isolated from IkkβWT (A) or IkkβMyeΔ/Δ (B) were cocultured with melanoma cells expressing RFP (3:1) for 5 hours and examined by confocal microscopy. Scale bars, magnification. C, macrophage killing activity of cells recovered after coculture in A and B were stained with 7-AAD and subjected to FACS analysis.
