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. 2014 Dec 19;14:195. doi: 10.1186/1471-2261-14-195

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© Wu et al.; licensee BioMed Central. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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The underlying of pathophysiological mechanisms related to aging exposure to SHS are depicted. Inflamm-aging changes lead to concentric LV hypertrophy transfer to eccentric LV hypertrophy.