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. 2015 Feb 15;15:22. doi: 10.1186/s12862-015-0281-9

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© Brunet et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Phylogenetic analysis of ADAMTS proteins. Phylogenetic analyses by maximum likelihood (ML) of all proteins of the ADAMTS family based on the shared structures, which are the metallopeptidase M12B, the disintegrin-like, and the thrombospondin (TSP) type-1 domain with the final spacer. The central part shows the general relationship of ADAMTS proteins among vertebrates and is detailed in Figure 2. Each major monophyletic group has a bootstrap value of 1000, and are detailed in the adjacent ML trees. Species are color coded: pink for primates, red for non-primate placentals, orange for marsupials and monotremes, green for sauropsids, dark green for amphibians, purple for the coelacanth, dark blue for the gar with teleostan fish shown in blue and additionally in cyan for genes showing a 3R-WGD. Full phylogenies of the colored and peripheral genes are available in Additional file 1: Figure S1a to Figure S1h.