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Secular trends of the proportion of patients who received an anti-thrombotic medication prescription 30 and 120 days preceding a hemorrhagic event
| Medication | Total | 1998-2001 | 2002-2005 | 2006-2008 | P value |
|---|---|---|---|---|---|
| Clopidogrel (30 days) | 4.2% | 1.7% | 4.3% | 7.0% | <0.001 |
| Clopidogrel (120 days) | 8.4% | 2.6% | 9.3% | 14.1% | <0.001 |
| Warfarin (30 days) | 16.6% | 17.5% | 17.5% | 14.3% | 0.316 |
| Warfarin (120 days) | 29.5% | 33.3% | 29.2% | 25.3% | 0.023 |
| Warfarin + Clopidogrel (120 days) | 1.8% | 0.7% | 1.6% | 3.4% | 0.072 |
