Table 1. Distribution of study population demographics and imaging parameters by imaging biomarkers in Cohort 1.
| Imaging biomarkers | ||||||||
|---|---|---|---|---|---|---|---|---|
| Entropy ratio | Tumor volume | Convexity | ||||||
| Characteristic 1 | No. | (%) | Mean | (SD) | Mean | (SD) | Mean | (SD) |
| Overall | 61 | (100.0) | 1.41 | (0.26) | 7884.6 | (11205.9) | 0.87 | (0.07) |
| Demographics | ||||||||
| Age at diagnosis | ||||||||
| < 65 | 20 | (32.8) | 1.42 | (0.05) | 11436.4 | (3651.2) | 0.87 | (0.02) |
| ≥ 65 | 41 | (67.2) | 1.40 | (0.04) | 6152.0 | (1129.7) | 0.86 | (0.01) |
| P-value | 0.834 | 0.084 | 0.829 | |||||
| Gender | ||||||||
| Female | 30 | (49.2) | 1.35 | (0.04) | 6467.9 | (1462.0) | 0.87 | (0.1) |
| Male | 31 | (50.8) | 1.46 | (0.05) | 9255.6 | (2444.3) | 0.87 | (0.1) |
| P-value | 0.102 | 0.336 | 0.995 | |||||
| Stage | ||||||||
| Stage I | 25 | (41.0) | 1.36 | (0.27) | 5875.2 | (10830.4) | 0.87 | (0.07) |
| Stage II | 19 | (31.2) | 1.44 | (0.24) | 9791.5 | (10927.1) | 0.86 | (0.09) |
| Stages III and IV | 17 | (27.8) | 1.42 | (0.25) | 8708.2 | (12217.9) | 0.87 | (0.07) |
| P-value | 0.590 | 0.493 | 0.817 | |||||
| Imaging Parameters | ||||||||
| Voltage, KvP | ||||||||
| 120 | 57 | (93.4) | 1.42 | (0.26) | 8187.2 | (11510.8) | 0.87 | (0.08) |
| 130 or 140 | 4 | (6.6) | 1.22 | (0.19) | 3572.3 | (3406.5) | 0.85 | (0.03) |
| P-value | 0.124 | 0.431 | 0.761 | |||||
| Convolution kernel | ||||||||
| B30F | 8 | (13.1) | 1.47 | (0.24) | 3314.3 | (4500.1) | 0.845 | (0.13) |
| B40f | 19 | (31.2) | 1.31 | (0.15) | 11752.4 | 1(5712.3) | 0.837 | (0.07) |
| B41F | 22 | (36.1) | 1.46 | (0.25) | 6487.3 | (7959.1) | 0.889 | (0.05) |
| Other 2 | 12 | (19.7) | 1.44 | 0.37) | 7369.0 | (10095.2) | 0.884 | (0.08) |
| P-value | 0.222 | 0.269 | 0.101 | |||||
| Slice thickness, mm | ||||||||
| <5.0 | 18 | (29.5) | 1.47 | (0.26) | 9836.8 | 0.844 | (0.10) | |
| ≥ 5.0 | 43 | (70.5) | 1.38 | (0.25) | 7067.4 | (11301.7) | 0.875 | (0.06) |
| P-value | 0.181 | 0.383 | 0.142 | |||||
| Pixel resolution 3 , mm | ||||||||
| < 0.6926 | 20 | (32.8) | 1.44 | (0.25) | 8013.6 | (10733.4) | 0.875 | (0.06) |
| ≥ 0.6926 to < 0.7785 | 20 | (32.8) | 1.36 | (0.21) | 10414.8 | (14356.6) | 0.878 | (0.09) |
| ≥ 0.7785 | 21 | (34.4) | 1.49 | (0.29) | 5352.1 | (7636.5) | 0.845 | (0.09) |
| P-value | 0.529 | 0.357 | 0.290 | |||||
1 96.7% (No. = 59) of this study population were ever smokers and 96.7% (No. = 59) were White race
2 Other includes B30s, B41s, B70s, CHST, FC01, FC13, LUNG, and STANDARD
3 Distribution based on the tertile values