Table 1. ASIV improves the cardiac hemodynamics in rats.
Group | LVEDP (mmHg) | LVSP (mmHg) | dP/dt (mmHg s−1) | −dP/dt (mmHg s−1) |
---|---|---|---|---|
Control | 7.9±0.7 | 128.5±2.2 | 6157.4±201.2 | 4352.1±220 |
Iso | 16.9±0.7** | 115.8±2.5** | 4340.5±213.8** | 3081.9±282.5** |
Iso+ASIV | 10.2±0.6 ## | 127.1±2.5 ## | 5648.4±177.8 ## | 4020.5±296.6 ## |
The cardiac hemohynamics were measured as described in Materials and Methods section. Data are presented as mean ±S.D. (n = 8).
**P<0.01 vs control;
## P<0.01 vs Iso.
LVEDP, Left ventricular end-diastolic pressure; LVSP, Left ventricular systolic pressure; +dp/dt, Maximal positive time derivative of developed pressure; −dp/dt, Maximal negative time derivative of developed pressure. Iso: Isoproterenol; ASIV: Astragaloside IV.