Table 3.
Univariate and multivariate analysis of clinicopathlogical parameters with overall survival (OS ) and recurrence-free survival(RFS) by Cox proportional hazards regression.
| Factors | Univeriate | Multivariate | ||||
|---|---|---|---|---|---|---|
| HR | 95%CI | P value | HR | 95%CI | P value | |
| OS | ||||||
| Age | 0.993 | 0.972-1.015 | 0.525 | |||
| Gender | 0.903 | 0.575-1.418 | 0.658 | |||
| Histology | 1.020 | 0.760-1.370 | 0.894 | |||
|
Site Size |
1.151 1.036 |
0.878-1.508 0.654-1.640 |
0.309 0.880 |
|||
| Clinical stage | 1.792 | 1.415-2.270 | 0.000* | 1.728 | 1.365-2.187 | 0.000* |
| GRHL2 | 0.481 | 0.291-0.793 | 0.004* | 0.545 | 0.329-0.902 | 0.018* |
| RFS | ||||||
| Age | 1.000 | 0.980-1.021 | 0.995 | |||
| Gender | 0.934 | 0.608-1.433 | 0.753 | |||
| Histology | 0.927 | 0.706-1.217 | 0.585 | |||
|
Site Size |
1.185 1.031 |
0.912-1.539 0.663-1.601 |
0.205 0.894 |
|||
| Clinical stage | 1.936 | 1.530-2.450 | 0.000* | 1.879 | 1.484-2.379 | 0.000* |
| GRHL2 | 0.522 | 0.326-0.837 | 0.007* | 0.601 | 0.374-0.967 | 0.036* |
*Statistically significant