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. 2015 Mar 3;36(3):343–352. doi: 10.1038/aps.2014.147

Figure 3.

Figure 3

Yhhu981 inhibited fatty acid synthesis in HepG2 cells. (A) HepG2 cells were incubated with yhhu981 at indicated concentration in serum-free media for 24 h, protein samples were prepared and subjected to Western blot. (B) HepG2 cells were incubated with yhhu981 at the indicated concentrations in serum-free media for 24 h, followed by the measurement of fatty acid synthesis. (C) HepG2 cells were pretreated with or without 10 μmol/L compound C for 30 min and then treated with 25 μmol/L yhhu981 or 1 mmol/L AICAR for another 24 h, followed by the measurement of fatty acid synthesis. AICAR treatment was used as a positive control. The results represent the mean±SEM for more than three independent experiments in duplicates. cP<0.01 compared with control. fP<0.01 compared with yhhu981 or AICAR treatment alone.