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. 2015 Jan 30;11(1):39–42. doi: 10.6026/97320630011039

Figure 1.

Figure 1

Flowchart of the functioning of the program SBION2. Upon start of the program it screens out NMR files if they are there in the working directory followed by making a list of X-ray structure files. The program verify for accessibility calculation program (ASA) in specified directory. If absent (i.e. NO), the program obtains atomic salt bridge pairs (step-1) and then converts them in residue specific salt bridge pairs (step-2). At this level four outputs are redirected (O-1). Output details of isolated (O-2) and networked salt-bridges (O-3) are separately reported (STEPs 3 to 6). A supplementary table (O-4) is prepared which includes both isolated and networked salt-bridge information (STEPs 5 and 6). If ASA (STEP 7) is YES, SBION2 performs step 1 through 6 that include core and surface location information of salt bridges along with earlier ones. Freq: Frequency; SMFS: Single bond multiplicity frequency and sum; MMF: Multiple bond multiplicity frequency; MMS: Multiple bond multiplicity sum; HB_SB: Hydrogen bonded salt-bridge frequency; non_HB: non-Hydrogen bonded salt-bridge frequency; SSD_SB: secondary structure (helix, sheet and coil) distribution of salt-bridge; L_SB: local salt-bridges; non_L: non-local salt bridges; II:_HSCI: intra- and interhelix, sheet and coil interactions; int_T: intervening residue table.