Table 1.
Baseline characteristics of the stable CAD population with angina in ADDITIONS according to PCI status
| Characteristic | Patients with previous PCI (n = 1,193) | Patients with no previous PCI (n = 1,126) |
|---|---|---|
| Demographic characteristics | ||
| Age (years) | 65.8 ± 9.9 | 66.0 ± 11.5 |
| Men | 803 (67%) | 547 (49%) |
| Body mass index (kg/m2) | 28.1 ± 4.3 | 28.5 ± 4.9 |
| Medical history | ||
| Previous PTCA with stent (PCI) | ||
| One | 669 (56%) | – |
| Two or more | 311 (26%) | – |
| Unknown | 213 (18%) | – |
| Previous myocardial infarction | 681 (58%) | 157 (13%) |
| Hypertension | 1,072 (90%) | 988 (88%) |
| Dyslipidemia | 889 (75%) | 638 (57%) |
| Diabetes mellitus | 409 (34%) | 368 (33%) |
| Peripheral artery disease | 125 (10%) | 79 (7%) |
| COPD | 171 (14%) | 173 (15%) |
| Asthma | 37 (3%) | 76 (7%) |
| Cardiovascular medication | ||
| Beta-blockers | 1,193 (100%) | 1,126 (100%) |
| ACE inhibitors | 698 (59%) | 500 (44%) |
| AT1 antagonists | 341 (29%) | 319 (28%) |
| Calcium antagonists | 244 (20%) | 185 (16%) |
| Long-acting nitrates/molsidomin | 374 (31%) | 204 (18%) |
| Ranolazine | 12 (1%) | 4 (<1%) |
| Diuretics | 477 (40%) | 398 (35%) |
| Aspirin | 1,059 (89%) | 804 (71%) |
| Clopidogrel | 336 (28%) | 84 (7%) |
| Statins | 1,001 (84%) | 689 (61%) |
| Clinical findings | ||
| Heart rate (bpm) | 83.1 ± 11.0 | 87.0 ± 13.2 |
| Weekly number of angina attacks | 1.9 ± 2.4 | 1.5 ± 2.0 |
| Weekly use of nitrates | 2.7 ± 3.7 | 1.8 ± 2.8 |
| Systolic blood pressure (mm Hg) | 135.1 ± 15.1 | 140.0 ± 16.1 |
| Diastolic blood pressure (mm Hg) | 81.5 ± 9.3 | 83.5 ± 9.5 |
| Ejection fraction (%) | 54.9 ± 12.9 | 57.2 ± 12.9 |
| Canadian Cardiovascular Society class | ||
| Class I | 214 (20%) | 391 (40%) |
| Class II | 609 (55%) | 452 (46%) |
| Class III | 264 (24%) | 139 (14%) |
| Class IV | 12 (1%) | 4 (<1%) |
| Quality of life | ||
| Visual analog scale | 56.2 ± 18.1 | 58.7 ± 18.5 |
| Quality of life index | 0.65 ± 0.28 | 0.68 ± 0.26 |
Values are presented as mean ± standard deviation or numbers and percentages (%)
Bpm beats per minute, CAD coronary artery disease, COPD chronic obstructive pulmonary disease, PCI percutaneous coronary intervention, PTCA percutaneous transluminal coronary angioplasty