Table 1.
Baseline patient characteristics and SF-12v2, SIBDQ, WPAI:SHP, and UC symptom scores for acute and maintenance phase samples and subsamples
| Acute phase baseline (n = 132) | Maintenance phase baseline (n = 206) | Maintenance phase baseline for acute + maintenance phase subsample (n = 56) | Maintenance phase baseline for maintenance phase-only subsample (n = 150) | |
|---|---|---|---|---|
| Age [mean (SD)] | 43.4 (14.1) | 46.9 (13.7) | 42.9 (14.4) | 48.4 (13.2)a |
| Female [n (%)] | 74 (56.1 %) | 106 (51.5 %) | 27 (48.2 %) | 79 (52.7 %) |
| Employed [n (%)] | 84 (63.6 %) | 150 (72.8 %) | 42 (75.0 %) | 108 (72.0 %) |
| SF-12v2 [mean (SD)] | ||||
| Physical functioning | 48.1 (10.1) | 53.5 (6.8) | 54.3 (4.4) | 53.2 (7.5) |
| Role physical | 44.8 (10.5) | 52.8 (6.7) | 53.0 (6.1) | 52.7 (6.9) |
| Bodily pain | 45.2 (11.3) | 53.6 (7.2) | 55.1 (6.1) | 53.1 (7.4) |
| General health | 44.6 (10.7) | 51.8 (7.8) | 52.4 (5.9) | 51.5 (8.5) |
| Vitality | 47.0 (10.3) | 53.6 (8.5) | 54.8 (8.8) | 53.2 (8.4) |
| Social functioning | 44.7 (12.4) | 52.9 (7.3) | 53.3 (7.0) | 52.8 (7.4) |
| Role emotional | 47.0 (10.7) | 51.7 (7.3) | 51.8 (7.5) | 51.6 (7.2) |
| Mental health | 48.1 (10.8) | 53.1 (8.6) | 54.3 (8.9) | 52.7 (8.4) |
| Physical summary (PCS) | 45.4 (9.8) | 53.2 (6.5) | 53.9 (4.4) | 53.0 (7.1) |
| Mental summary (MCS) | 47.3 (10.1) | 52.3 (8.2) | 53.0 (8.6) | 52.1 (8.0) |
| SIBDQ [mean (SD)] | ||||
| Bowel symptoms | 12.8 (4.3) | 18.5 (2.6) | 18.6 (2.4) | 18.4 (2.7) |
| Systemic symptoms | 8.9 (3.0) | 10.8 (2.5) | 11.2 (2.6) | 10.6 (2.6) |
| Emotional function | 14.0 (4.3) | 17.3 (3.0) | 17.4 (3.3) | 17.2 (2.9) |
| Social function | 10.1 (3.4) | 13.2 (1.5) | 13.2 (1.5) | 13.2 (1.5) |
| Total score | 45.9 (12.9) | 59.8 (7.7) | 60.7 (7.5) | 59.4 (7.8) |
| WPAI [mean (SD)] | ||||
| Absenteeism | 8.8 (21.1) | 0.6 (3.5) | 1.4 (5.9) | 0.3 (1.7) |
| Presenteeism | 27.5 (26.3) | 5.1 (9.7) | 5.2 (11.3) | 5.1 (9.1) |
| Overall work impairment | 30.0 (29.2) | 5.5 (10.8) | 6.1 (13.7) | 5.3 (9.6) |
| Activity impairment | 35.5 (31.2) | 7.6 (14.1) | 6.6 (14.4) | 8.0 (14.0) |
| UC symptoms [mean (SD)] | ||||
| Stool frequency | 0.73 (0.69) | 0.15 (0.33) | 0.15 (0.38) | 0.14 (0.31) |
| Rectal bleeding severity | 0.88 (0.77) | 0.02 (0.12) | 0.02 (0.11) | 0.03 (0.12) |
SF-12v2 12-item Short-Form Health Survey, version 2, SIBDQ Short Inflammatory Bowel Disease Questionnaire, WPAI:SHP Work Productivity and Activity Impairment: Specific Health Problem, UC ulcerative colitis, SD standard deviation
a P < 0.05 for differences between acute + maintenance phase and maintenance phase-only subsamples