Table 5.

Comparison of Mean SF-12v2, SIBDQ, WPAI:SHP, and UC symptom scores from baseline to week 8 of the acute phase

	N	Baseline [mean (SE)]	Week 8 [mean (SE)]	Mean difference	P a	Effect size (d z)
SF-12v2
Physical functioning	107	49.1 (0.88)	51.2 (0.76)	2.1	<0.01	0.27
Role physical	107	45.8 (0.95)	49.4 (0.85)	3.6	<0.001	0.40
Bodily pain	107	46.5 (1.01)	51.1 (0.95)	4.6	<0.001	0.45
General health	107	45.3 (1.03)	48.6 (0.91)	3.3	<0.01	0.32
Vitality	107	47.7 (0.99)	51.8 (0.90)	4.1	<0.001	0.38
Social functioning	107	45.7 (1.13)	49.4 (0.98)	3.7	<0.01	0.31
Role emotional	107	48.3 (0.90)	49.8 (0.93)	1.5	ns	0.15
Mental health	107	49.0 (0.97)	52.5 (0.93)	3.5	<0.001	0.36
PCS	107	46.4 (0.89)	49.8 (0.81)	3.4	<0.001	0.45
MCS	107	48.2 (0.91)	51.1 (0.88)	2.9	<0.01	0.29
SIBDQ
Bowel symptoms	103	13.2 (0.43)	17.2 (0.35)	4.0	<0.001	1.03
Systemic symptoms	103	9.2 (0.3)	10.6 (0.26)	1.4	<0.001	0.47
Emotional function	103	14.6 (0.41)	16.4 (0.37)	1.8	<0.001	0.44
Social function	103	10.5 (0.32)	12.1 (0.27)	1.6	<0.001	0.55
Total score	103	47.5 (1.24)	56.3 (1.05)	8.8	<0.001	0.79
WPAI:SHP
Absenteeism	70	6.8 (2.18)	2.8 (1.54)	–4.0	<0.05	0.26
Presenteeism	69	25.2 (2.95)	12.9 (2.59)	–12.3	<0.001	0.46
Work productivity	69	27.4 (3.25)	13.6 (2.71)	–13.8	<0.001	0.47
Activity impairment	103	32.4 (2.97)	18.2 (2.54)	–14.2	<0.001	0.52

SF-12v2 12-item Short-Form Health Survey, version 2, SIBDQ Short Inflammatory Bowel Disease Questionnaire, WPAI:SHP Work Productivity and Activity Impairment: Specific Health Problem, BMI body mass index, SE standard error of the mean, ns not statistically significant

^a P values for comparison of means between visits were derived from paired-sample t tests with a two-tailed test for statistical significance