Fig. 2.

Study design for PICV infection of Syrian golden hamsters and lung viral titers. A At D0, three uninfected hamsters were euthanized to serve as baseline controls. The remaining hamsters were challenged with 300 PFU of PICV and euthanized in groups of three at D1, D3, D5, and D7. B Lung tissue was processed and titrated for PICV as described in Materials and Methods. Samples were titrated three times on three different days. Results are plotted as the average ± one standard deviation.