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. 2015 Feb 15;5(5):515–529. doi: 10.7150/thno.10319

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(A-D) Selected images from a 3D gradient echo dataset from the MC38 (colorectal) subcutaneous tumour model, averaged over the 4 echoes. Images acquired pre- (A) and (B) and post- (C) and (D) injection of c(RGDyK)-MPIO or c(RADyK)-MPIO, respectively. (E-F) Graphs showing paired analysis of hypointensity volumes from c(RGDyK)-MPIO (E) and c(RADyK)-MPIO (F) treated animals. Data are expressed as a ratio of the volume of MPIO-induced hypoinintensity vs. the total tumour volume. (G-H) 3D reconstructions of hypointesities induced by c(RGDyK)-MPIO (G) or c(RADyK)-MPIO (H). **P < 0.005, ***P < 0.0005.