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. Author manuscript; available in PMC: 2016 Mar 3.
Published in final edited form as: Cell Metab. 2015 Mar 3;21(3):455–467. doi: 10.1016/j.cmet.2015.02.004

Figure 2. LncLSTR knockdown reduces plasma TG levels in mice.

Figure 2

(A) Expression levels of lncLSTR in the livers of control and lncLSTR KD mice received shRNA adenoviruses for LacZ (LacZ sh) and lncLSTR (lncLSTR sh) respectively (n=6).

(B) Plasma TG levels in lncLSTR KD (lncLSTR sh) and control (LacZ sh) mice (n=7) after a 6-hour fast (6h Fast), a 24-hour fast (24h Fast), or 6-hour refeeding after a 24-hour fast (6h Refeed,).

(C) TG secretion rates in lncLSTR KD and control mice (n=6) determined by administration of Poloxamer-407 to block TG uptake.

(D) Plasma TG levels in lncLSTR KD and control mice (n=7) orally receiving olive oil.

(E) Plasma TG levels in control (n=8) and lncLSTR KD (n=7) ApoE−/− mice.

Error bars represent SEM, *p<0.05.