Bioinformatic analysis of the methylated proteins.
A, Pie chart of predicted subcellular localization of the methylated proteins according to the PENCE Proteome Analyst databases. Proteins predicted to be present in the “ribosome” and “spliceosome” were differentiated from those predicted to be in the “cytoplasm.” Proteins were designated “other” if their localizations or functions were not annotated in the database. B, Pie chart of Molecular Function analysis of the methylated proteins analyzed with DAVID (The Database for Annotation, Visualization, and Integrated Discovery). C–F, Representative protein complexes enriched in monomethyllysine proteome by querying CORUM database (39).