Figure 4. Decreased expression of bile acid synthesis genes contributes to altered gallbladder bile acid composition of LKO mice.
(a) Dot plot of hepatic bile acid synthesis genes expression of the LKO and LWT mice on the LFnC diet (n = 5). (b) Relative gallbladder bile acid composition (n = 8–11) of the mice on the LFnC diet. (c) Plasma lipids profile (n = 8) and corticosterone levels (n = 5–6) of the LWTs and LKOs on the LFnC diet. Columns represent means and error bars represent SEMs. AU – arbitrary units. * p < 0.05;· p < 0.1.