Figure 3. Differences between the wild type and mutant PC4 in the protein-DNA interface.

Schematic illustrations (Ligplot+) of the protein-DNA contacts around residue 89 in the W89Y mutant (a) and wild type (b) of the PC4-DNA complexes. The conformation of residues around position 89 in the wild type and W89Y mutant DNA complex (c). The water molecules in this region are coloured in grey and blue for the wild type and mutant complexes, respectively.